Adrenergic-melatonin heteroreceptor complexes are key in controlling ion homeostasis and intraocular eye pressure and their disruption contributes to hypertensive glaucoma
H. A. Alkozi, G. Navarro, D. Aguinaga, I. Reyes-Resina, J. Sanchez-Naves, M. J. Perez de Lara, R. Franco, J. J. Pintor
The paper shows that disruption of adrenergic-melatonin receptor complexes contributes to glaucoma by affecting ion homeostasis and intraocular pressure, and suggests a therapeutic approach using melatonin and prazosin.
bioRxiv · May 14, 2019Physiology