Mechanism of RPA-Facilitated Processive DNA Unwinding by the Eukaryotic CMG Helicase
H. B. Kose, S. Xie, G. Cameron, M. S. Strycharska, H. Yardimci
This study investigates how RPA enhances CMG helicase activity by preventing dsDNA engagement and facilitating processive DNA unwinding at the replication fork.
bioRxiv · Oct 7, 2019 · PreprintBiochemistry