Aldh2 is a lineage-specific metabolic gatekeeper in melanocyte stem cells
H. Brunsdon, A. Brombin, S. Peterson, J. H. Postlethwait, E. E. Patton
The paper identifies Aldh2 as a metabolic gatekeeper in zebrafish melanocyte stem cells during regeneration, showing it enables formate production for nucleotide biosynthesis.
bioRxiv · Sep 23, 2021Cell Biology