Author

H. C. Drexler

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Biochemistry· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Eggers· 1 shared C. Fufezan· 1 shared C. Kraft· 1 shared F. Mollet· 1 shared H. Mancilla· 1 shared H. R. Scholer· 1 shared J. M. Bruder· 1 shared J. Wu· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

C. Eggers

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1 paper

Recent·Most cited

tRNA modifications tune decoding of codon pairs to prevent cellular quality control responses

J. Wu, C. Eggers, O. Sin, L. Koziej, H. Mancilla, F. Mollet, H. R. Scholer, H. C. Drexler, T. Ranff, C. Fufezan, C. Kraft, S. Glatt, J. M. Bruder, S. A. Leidel

This study shows that tRNA modifications affect codon pair decoding, leading to ribosome stalling and triggering quality control responses to prevent protein aggregation.

bioRxiv · Feb 27, 2024 · PreprintBiochemistry