Author

H. C. Hartzell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Assay:electrophysiology· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

K. Yu· 2 shared E. Tajkhorshid· 1 shared H. Choo· 1 shared H. J. Choo· 1 shared H. Yang· 1 shared L. Encarnacion-Rivera· 1 shared P. Liang· 1 shared S. Foltz· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBiophysics

K. Yu

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Author profile →

4 papers

Recent·Most cited

Niclosamide potentiates TMEM16A and induces vasoconstriction

P. Liang, Y. C. S. Wan, K. Yu, H. C. Hartzell, H. Yang

This study shows niclosamide potentiates TMEM16A and induces vasoconstriction, challenging its use as a TMEM16A inhibitor for asthma and COPD.

bioRxiv · Jul 31, 2023Biophysics

Defective Trafficking of Annexins to the Site of Injury in ANO5-Knockout Muscle Fibers

S. J. Foltz, Y. Y. Cui, H. J. Choo, H. C. Hartzell

This study shows that ANO5 deficiency disrupts annexin trafficking to the injury site in muscle fibers, leading to impaired membrane repair and prolonged calcium elevation.

bioRxiv · May 22, 2020 · PreprintCell Biology

A Network of Phosphatidylinositol 4,5-bisphosphate Binding Sites Regulate Gating of the Ca2+-activated Cl- Channel ANO1 (TMEM16A)

K. Yu, T. Jiang, Y. Cui, E. Tajkhorshid, H. C. Hartzell

This study identifies three PI(4,5)P2 binding sites on ANO1 that allosterically regulate its Ca2+-activated Cl- channel gating through molecular dynamics and electrophysiology.

bioRxiv · Jul 25, 2019Biophysics

Myosoft: an automated muscle histology analysis tool using machine learning algorithm utilizing FIJI/ImageJ software.

L. Encarnacion-Rivera, S. Foltz, H. C. Hartzell, H. Choo

Myosoft automates muscle histology analysis using machine learning in FIJI/ImageJ, providing faster and more accurate results than manual methods.

bioRxiv · Jul 16, 2019Physiology