Author

H. C. Leeson

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Cell Biology· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Mackay-Sim· 1 shared A. Taherian Fard· 1 shared C. Gomez-Inclan· 1 shared E. J. Wolvetang· 1 shared H. K. Chaggar· 1 shared J. Aguado· 1 shared M. F. Lavin· 1 shared Z. Hunter· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

A. Mackay-Sim

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1 paper

Recent·Most cited

Ataxia Telangiectasia patient-derived neuronal and brain organoid models reveal mitochondrial dysfunction and oxidative stress

H. C. Leeson, J. Aguado, C. Gomez-Inclan, H. K. Chaggar, A. Taherian Fard, Z. Hunter, M. F. Lavin, A. Mackay-Sim, E. J. Wolvetang

This study uses patient-derived iPSCs and organoids to show mitochondrial dysfunction and oxidative stress in AT, which can be mitigated by ATM correction or antioxidants.

bioRxiv · Jan 29, 2024Cell Biology