Author

E. J. Wolvetang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. C. Mar· 2 shared A. J. Davidson· 1 shared A. J. van Waardenberg· 1 shared A. Laslett· 1 shared A. Mackay-Sim· 1 shared A. Przepiorski· 1 shared A. Taherian Fard· 1 shared C. Gomez-Inclan· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersMicrobiology

J. C. Mar

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Ataxia Telangiectasia patient-derived neuronal and brain organoid models reveal mitochondrial dysfunction and oxidative stress

H. C. Leeson, J. Aguado, C. Gomez-Inclan, H. K. Chaggar, A. Taherian Fard, Z. Hunter, M. F. Lavin, A. Mackay-Sim, E. J. Wolvetang

This study uses patient-derived iPSCs and organoids to show mitochondrial dysfunction and oxidative stress in AT, which can be mitigated by ATM correction or antioxidants.

bioRxiv · Jan 29, 2024Cell Biology

Inhibition of host N-myristoylation compromises the infectivity of SARS-CoV-2 due to Golgi-bypassing egress from lysosomes and endoplasmic reticulum

S. H. Saber, M. R. Shaker, J. Sng, N. Yak, S. D. Morrison, S. Pars, H. Zheng, G. Pietrogrande, T. Binder, S. Lu, M. Floetenmeyer, R. Ojha, T. Quirin, J. Ruuska, T. Smura, , M. Joensuu

This study shows that inhibiting host N-myristoylation reduces SARS-CoV-2 infectivity by impairing viral envelope protein maturation and causing Golgi-bypassing egress.

bioRxiv · Mar 3, 2023 · PreprintMicrobiology

Substrate stiffness facilitates improved induced pluripotent stem cell production through modulation of both early and late phases of cell reprogramming

M. M. Chowdhury, S. Samuel Zimmerman, H. Leeson, C. Nefzger, J. C. Mar, A. Laslett, J. M. Polo, E. J. Wolvetang, J. J. Cooper-White

This study shows that medium stiffness substrates enhance iPSC production by improving both early and late reprogramming phases, leading to higher numbers and better quality iPSCs.

bioRxiv · Feb 27, 2023 · PreprintBioengineering

Use of human iPSCs and kidney organoids to develop a cysteamine/mTOR inhibition combination therapy to treat cystinosis

J. A. Hollywood, A. Przepiorski, P. T. Harrison, E. J. Wolvetang, A. J. Davidson, T. M. Holm

This study uses human iPSCs and kidney organoids to show that combining cysteamine and mTOR inhibition improves cystinosis treatment by correcting multiple disease phenotypes.

bioRxiv · Apr 1, 2019Pathology

Platypus Induced Pluripotent Stem Cells: the Unique Pluripotency Signature of a Monotreme

D. J. Whitworth, I. Limnios, M. Gauthier, P. Weeratunga, D. Ovchinnikov, G. Baillie, S. Grimmond, J. Graves, E. J. Wolvetang

The paper generates platypus induced pluripotent stem cells and shows SOX2 replaced SOX3 in the pluripotency network in primitive mammals.

bioRxiv · Jul 25, 2018Cell Biology