Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of \"quasi-ordered\" states.
A. F. Clouser, H. E. Baughman, B. Basanta, M. Guttman, A. Nath, R. E. Klevit
This study characterizes the disordered N-terminal region of HSPB1 using hybrid methods, revealing quasi-ordered states and their role in HSPB1 function and disease.
bioRxiv · Aug 29, 2019Biochemistry