Author

H. F. Alkan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1

Frequent Co-Authors

H. Hackl· 2 shared J. Bogner-Strauss· 2 shared M. Vander Heiden· 2 shared G. Hoefler· 1 shared J. Fosselteder· 1 shared K. E. Walter· 1 shared M. Pichler· 1 shared P. Vesely· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersCancer Biology

H. Hackl

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2 papers

Recent·Most cited

Loss of malate-aspartate shuttle component SLC25A12 induces pulmonary metastasis

H. F. Alkan, P. Vesely, H. Hackl, J. Fosselteder, M. Vander Heiden, M. Pichler, G. Hoefler, J. Bogner-Strauss

This study shows that loss of SLC25A12 reduces cytosolic aspartate and impairs tumor growth and metastasis in vivo, but not in vitro.

bioRxiv · May 29, 2020Cancer Biology

N-acetylaspartate improves cell survival when glucose is limiting

H. F. Alkan, K. E. Walter, H. Hackl, M. Vander Heiden, T. Madl, J. Bogner-Strauss

The paper shows N-acetylaspartate (NAA) supports cell survival in low-glucose conditions by maintaining UDP-GlcNAc levels and reducing ER stress, independent of its breakdown into aspartate or acetate.

bioRxiv · May 28, 2020 · PreprintCancer Biology