Cell BiologybioRxivPreprint
IL-1β inhibition partially negates the beneficial effects of diet-induced lipid lowering
S. Karnewar, V. KARNEWAR, R. A. Deaton…·G. K. Owens
This study shows that inhibiting IL-1β in mice reduces the beneficial effects of diet-induced lipid lowering on atherosclerosis, increasing plaque burden and decreasing plaque stability.