Platinum-Induced Mitochondrial OXPHOS Contributes to Cancer Stem Cell Enrichment in Ovarian Cancer
S. Sriramkumar, R. Sood, T. D. Huntington, A. H. Ghobashi, W. Wang, K. P. Nephew, H. M. OHagan
This study shows platinum treatment increases mitochondrial activity and OXPHOS in ovarian cancer cells, leading to enrichment of cancer stem cells, which can be blocked by OXPHOS inhibitors.
bioRxiv · Feb 1, 2022Cancer Biology