BiochemistrybioRxiv
Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation
L. Zhang, M. Mann, Z. Syed…·K. G. Ten Hagen
This study shows that O-glycosylation near the furin cleavage site of SARS-CoV-2 spike protein reduces furin cleavage and is mediated by GALNT enzymes and a proline at position 681.
DOI 10.1073/pnas.2109905118