Author

K. G. Ten Hagen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

L. Zhang· 2 shared C. K. E. Bleck· 1 shared D. C. Zeldin· 1 shared D. T. Tran· 1 shared E. Tian· 1 shared H. M. Reynolds· 1 shared L. A. Tabak· 1 shared M. Mann· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

L. Zhang

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Author profile →

2 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 16, 2021

Orchestrated Restructuring Events During Secretory Granule Maturation Mediate Intragranular Cargo Segregation

Z. A. Syed, L. Zhang, D. T. Tran…·K. G. Ten Hagen

This study identifies intragranular restructuring events during secretory granule maturation that mediate cargo segregation and reveals genes and factors involved in these processes.

DOI 10.1101/2021.08.16.456250

genetic perturbation / CRISPRmicroscopy & imaging analysis

𝕏 PostBluesky

BiochemistrybioRxivFeb 5, 2021

Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation

L. Zhang, M. Mann, Z. Syed…·K. G. Ten Hagen

This study shows that O-glycosylation near the furin cleavage site of SARS-CoV-2 spike protein reduces furin cleavage and is mediated by GALNT enzymes and a proline at position 681.

DOI 10.1073/pnas.2109905118

humanexperimental assay

𝕏 PostBluesky