Tethering by Uso1 is dispensable: The Uso1 monomeric globular head domain interacts with SNAREs to maintain viability.
I. Bravo-Plaza, V. G. Tagua, H. N. Arst, A. Alonso, M. Pinar, B. Monterroso, A. Galindo, M. A. Penalva
This study shows that the Uso1 monomeric globular head domain can maintain viability by interacting with SNAREs, bypassing the need for RAB1-mediated tethering.
bioRxiv · Nov 30, 2022Cell Biology