A. Alonso

Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases

This study shows that human APOBEC3B causes tumor heterogeneity and metastases in mice, with increased C-to-T mutations and structural variations.

LC3 subfamily in cardiolipin-mediated mitophagy: A comparison of the LC3A, LC3B and LC3C homologs

The paper compares LC3A, LC3B, and LC3C interactions with cardiolipin in mitophagy, finding LC3A binds more strongly and recognizes oxidized cardiolipin, while LC3C shows less specific binding.

Tethering by Uso1 is dispensable: The Uso1 monomeric globular head domain interacts with SNAREs to maintain viability.

This study shows that the Uso1 monomeric globular head domain can maintain viability by interacting with SNAREs, bypassing the need for RAB1-mediated tethering.

Phase behaviour of C18-N-acyl sphingolipids, the prevalent species in human brain

This study investigates the phase behavior of C18-N-acyl sphingolipids in brain tissue, showing they form rigid domains and contribute to membrane tightness.

Climatic niche pre-adaptation in mainland Europe facilitated the colonization of Madeira by ivies (Hedera L., Araliaceae)

The study evaluates how climatic niche pre-adaptation in mainland European ivies facilitated their colonization of Madeira, showing a nested phylogeny and adaptive trait similarity between H. maderensis and H. iberica.

CHO/LY-B cell growth under limiting sphingolipid supply: correlation between lipid composition and biophysical properties of sphingolipid-restricted cell membranes

This study examines how sphingolipid restriction affects LY-B cell membrane properties, showing reduced membrane rigidity and altered lipid composition.

Translational control of MPS1 links protein synthesis with the initiation of cell division and spindle pole body duplication in Saccharomyces cerevisiae

The paper shows that a uORF in the MPS1 gene represses Mps1p synthesis, linking protein synthesis to cell cycle progression and spindle pole body duplication in yeast.

The Hex-Maze: A previous knowledge and schema task for mice

The paper introduces a spatial navigation task for mice, the Hex-Maze, to study how previous knowledge (schema) influences learning and memory consolidation over time.

High throughput droplet single-cell Genotyping of Transcriptomes (GoT) reveals the cell identity dependency of the impact of somatic mutations

This study introduces GoT, a high-throughput method linking single-cell genotypes and transcriptomes, revealing that somatic mutations' transcriptional effects depend on cell identity.