Interferon-gamma is Quintessential for NOS and COX Expression in ER- Breast Tumors that Lead to Poor Outcome
R. Y. Cheng, L. A. Ridnourl, A. L. Wink, A. L. Gonzalez, E. L. Femino, H. Rittscher, V. Somasundarum, W. F. Heinz, L. Coutinho, C. Rangel, E. f. Edmondson, D. Butcher, R. J. Kinders, X. Li, S. T. Wong, , D. A. Wink
The paper shows IFN-gamma induces NOS2 and COX2 in ER-breast tumors, linked to poor outcomes, through spatial analysis of tumor microenvironments.
bioRxiv · Apr 6, 2023Cancer Biology