S. T. Wong

Spatial analysis of NOS2 and COX2 interaction with T-effector cells reveals immunosuppressive landscapes associated with poor outcome in ER- breast cancer patients

The paper identifies spatial interactions between NOS2, COX2, and T-effector cells in ER- breast cancer, linking these patterns to poor patient outcomes and suggesting potential therapeutic strategies.

NOS2 and COX2 Provide Key Spatial Targets that Determine Outcome in ER- Breast Cancer

This study identifies NOS2 and COX2 as key spatial targets in ER- breast cancer that influence immune phenotypes and clinical outcomes through spatial analysis of tumor microenvironments.

Immunosuppressive tumor microenvironment of osteosarcoma

This study identifies immunosuppressive mechanisms in osteosarcoma using single-cell and spatial transcriptomics, revealing interactions between MDSCs, T-cells, and tumor cells that promote an immunosuppressive microenvironment.

Interferon-gamma is Quintessential for NOS and COX Expression in ER- Breast Tumors that Lead to Poor Outcome

The paper shows IFN-gamma induces NOS2 and COX2 in ER-breast tumors, linked to poor outcomes, through spatial analysis of tumor microenvironments.

Long-term ovarian cancer survivors: spatial transcriptomics depict ligand-receptor crosstalk heterogeneity at the tumor-stroma interface

NOS2 and COX2 Blockade Limits TNBC Disease Progression and Alters CD8+ T Cell Spatial Orientation and Density

This paper shows that blocking NOS2 and COX2 reduces TNBC tumor growth and improves CD8+ T cell infiltration and spatial distribution in tumors.

imageseg: an R package for deep learning-based image segmentation

The paper introduces an R package for deep learning-based image segmentation, demonstrating its utility in ecological applications with high accuracy models for forest structure.

Habitat-Net: Segmentation of habitat images using deep learning

Habitat-Net segments tropical rainforest habitat images using deep learning, achieving higher accuracy and faster processing than manual methods and U-Net.

Shifting up a gear with iDNA: from mammal detection events to standardized surveys

The paper compares iDNA and camera-trap surveys to assess mammal occupancy in tropical rainforests, finding consistent results and suggesting iDNA as a viable complementary method.