Revisiting the origin of interleukin 1 (IL-1) based on biological activities of IL-1 in anamniotes and their sub-functionalization in amniotes
E. Hasel de Carvalho, E. Bartok, H. Stoelting, B. Bajoghli, M. Leptin
The paper investigates the evolutionary origin of IL-1 by comparing its biological activities in anamniotes and amniotes, finding sub-functionalization in mammals.
bioRxiv · Feb 15, 2022 · PreprintImmunology