The EGFR-STYK1-FGF1 axis sustains functional drug tolerance to EGFR inhibitors in EGFR-mutant non-small cell lung cancer
C. Eggermont, P. Giron, M. Noeparast, H. Vandenplas, P. Aza-Blanc, G. J. Gutierrez, J. De Greve
This study identifies STYK1 as a target that enhances the effects of EGFR inhibition in NSCLC cells, suggesting co-targeting EGFR and STYK1 may improve treatment outcomes.
bioRxiv · Apr 26, 2022Cancer Biology