Author

H. W.-S. Tan

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

G. Lu· 1 shared H.-M. Shen· 1 shared J. Chen· 1 shared J. Yi· 1 shared K. Mallilankaraman· 1 shared P. Chen· 1 shared Q. Yang· 1 shared Q. Yu· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

G. Lu

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1 paper

Recent·Most cited

Synthetic lethality targeting LKB1 mutant and EGFR wild type human non-small cell lung cancer cells by glucose starvation and SGLT2 inhibition

Y. Ren, J. Chen, X. Mo, Q. Yang, P. Chen, G. Lu, H. W.-S. Tan, J. Yi, Q. Yu, Y.-S. Kim, K. Mallilankaraman, H.-M. Shen

This study identifies glucose starvation and SGLT2 inhibition as synthetic lethal strategies for EGFR-WT/LKB1-mutant NSCLC, showing efficacy in xenograft models.

bioRxiv · Apr 29, 2019 · PreprintCancer Biology