Engineering bacterial protein polymers to support human pluripotent stem cell growth and differentiation in culture.
A. Creigh, H. Waller, J. H. Lakey, Z. M. Chrzanowska-Lightowlers, R. N. Lightowlers, D. T. Peters
This study develops Caf1 protein variants that support iPSC growth and differentiation as effectively as GelTrex, offering a defined and cost-effective alternative to animal-derived substrates.
bioRxiv · Apr 29, 2024 · PreprintBioengineering