De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis
T. Laval, L. Pedro-Cos, W. Malaga, L. Guenin-Mace, A. Pawlik, V. Mayau, H. Yahia-Cherbal, W. Frigui, J. Bertrand-Michel, C. Guilhot, C. Demangel
This study shows that Mycobacterium tuberculosis uses host-derived arachidonic acid, a polyunsaturated fatty acid, for growth and immune evasion.
bioRxiv · Jul 8, 2021Immunology