Cyclic loading regime considered beneficial does not protect injured and interleukin-1-inflamed cartilage from post-traumatic osteoarthritis
A. S. A. Eskelinen, C. Florea, P. Tanska, H.-H. K. Hung, E. H. Frank, S. Mikkonen, P. Nieminen, P. Julkunen, A. J. Grodzinsky, R. K. Korhonen
This study shows that cyclic loading does not protect injured and interleukin-1-inflamed cartilage from post-traumatic osteoarthritis and may even promote its progression over time.
bioRxiv · Aug 23, 2021Pathology