P. Tanska

Injury-related cell death and proteoglycan loss in articular cartilage: Numerical model combining necrosis, reactive oxygen species, and inflammatory cytokines

This paper develops a 2-D mechanobiological model to simulate early post-traumatic osteoarthritis by integrating necrosis, reactive oxygen species, and inflammatory cytokines, showing partial recovery of proteoglycan content when inflammation is mitigated.

Associations of human femoral condyle cartilage structure and composition with viscoelastic and constituent-specific material properties at different stages of osteoarthritis

This study examines how structural and compositional changes in human knee cartilage relate to mechanical properties across osteoarthritis stages.

A musculoskeletal finite element model of rat knee joint for evaluating cartilage biomechanics during gait

This paper develops a musculoskeletal finite element model of a rat knee joint to study cartilage biomechanics during gait, revealing compartment-specific stress and strain patterns.

Cyclic loading regime considered beneficial does not protect injured and interleukin-1-inflamed cartilage from post-traumatic osteoarthritis

This study shows that cyclic loading does not protect injured and interleukin-1-inflamed cartilage from post-traumatic osteoarthritis and may even promote its progression over time.

An EMG-assisted Muscle-Force Driven Finite Element Analysis Pipeline to Investigate Joint- and Tissue-Level Mechanical Responses in Functional Activities: Towards a Rapid Assessment Toolbox

This paper introduces and validates a semi-automated MS-FE modeling pipeline using EMG data to estimate joint and tissue-level knee mechanics in KOA patients during daily activities.