Unbiased lineage tracing across the adipose organ decouples developmental origin from anatomical and transcriptomic identities
O. Inoue, A. Singh, M. Ginugu, C. Ahn, M. A. Secchi, S. J. Bowling, H.-W. Lim, Joan Sanchez-Gurmaches
This study uses CRISPR-mediated lineage tracing to show that adipose depot identity is shaped by anatomical niche rather than embryonic lineage.
bioRxiv · Nov 9, 2026 · PreprintDevelopmental Biology