TMEM145 is a key component in stereociliary link structures of outer hair cells
Jae Won Roh, Kyung Seok Oh, Jiahn Lee, Yujin Choi, Soomin Kim, Ji Won Hong, Yelim Kim, Hogun Lew, Seung Hyun Jang, Hae-Sol Shin, Jiyeon Ohk, Hosung Jung, Kyoung Yul Seo, Jinwoong Bok, Chul Hoon Kim, Heon Yung Gee
This study identifies TMEM145 as a critical transmembrane protein in OHC stereociliary structures, showing its necessity for structural integrity and auditory function.
bioRxiv · Feb 10, 2025 · PreprintNeuroscience