Cannabinoid receptor 1 positive allosteric modulator ZCZ011 shows differential effects on behavior and the endocannabinoid system in HIV-1 Tat transgenic female and male mice
Barkha J. Yadav-Samudrala, Hailey Dodson, Shreya Ramineni, Elizabeth Kim, Justin L. Poklis, Dai Lu, Bogna Marta Ignatowska-Jankowska, Aron H. Lichtman, Sylvia Fitting
This study evaluates the effects of ZCZ011, a CB1R PAM, on behavior and the endocannabinoid system in HIV-1 Tat transgenic mice, showing sex- and genotype-dependent outcomes.
PLoS ONE · Jun 24, 2024Peer-reviewedNeuroscience