Porcine Left Atrial and Ventricular Thick Filaments Exhibit Distinct Resting Structures and Calcium-dependent Responses
Lin Qi, Maicon Landim-Vieira, Hailey Flannagan, Marcela Monroy, Edward O Olaniyan, Meihua Guo, Chengqian Gao, Shengyao Yuan, Henry M. Gong, Suman Nag, Thomas C. Irving, Weikang Ma
This study compares the structural and functional properties of porcine left atrial and ventricular myosin filaments, revealing distinct calcium-dependent regulatory mechanisms between the two chambers.
bioRxiv · May 20, 2026 · PreprintPhysiology