CLCC1 promotes membrane fusion during herpesvirus nuclear egress.
Bing Dai, Adrian W. Sperl, Lucas Polack, Isabel Mejia, Haley Dame, Tien Huynh, Chloe Deveney, Nathalie Lavoie, Chanyoung Lee, John G. Doench, Matthew D. Daugherty, Ekaterina E. Zheleznova Heldwein
The paper identifies CLCC1 as a host factor essential for herpesvirus nuclear egress fusion, showing its role in membrane fusion and nuclear envelope morphogenesis.
Nature Communications · Nov 21, 2025Peer-reviewedMicrobiology