Impaired hippocampal circuit function underlying memory encoding and consolidation precede robust Aβ deposition in a mouse model of Alzheimer's disease
Hanyan Li, Zhuoyang Zhao, Aline Fassini, Han K. Lee, Reese J. Green, Stephen N. Gomperts
The paper identifies impaired hippocampal circuit function in a mouse model of Alzheimer's disease before Aβ deposition, highlighting issues in theta-gamma oscillations and place cell reactivation during sleep.
Scientific Reports · Jul 1, 2025Peer-reviewedNeuroscience