Author

Aline Fassini

Harvard UniversityORCID 0000-0002-9523-9342Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Assay:electronic health records· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Stephen N. GompertsiD· 2 shared Alin Asim· 1 shared Allison E. GreueliD· 1 shared Anand K. GanesaniD· 1 shared Andrea BallabioiD· 1 shared Andrew M. MuiD· 1 shared Bradley T. HymaniD· 1 shared David E. FisheriD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Stephen N. GompertsORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

UV induces common cutaneous amyloid-like melanosomal protein aggregates

Nicholas Theodosakis, Porter B Howland, Miroslav Hejna, Stephen M. Ostrowski, Talya Cohen-Neamie, Remi Joseph, Helen Ji, Allison E. Greuel, Judth R. Boozer, Mariam Y. Demian, Alin Asim, Khanh Nguyen, Andrew M. Mu, Philip A. Seifert, Konrad Kaminiów, , David E. Fisher

The paper shows UV exposure causes misfolded melanosomal proteins to aggregate, contributing to skin pigmentation disorders and melanocyte dysfunction.

bioRxiv · Dec 18, 2025 · PreprintMolecular Biology

Impaired hippocampal circuit function underlying memory encoding and consolidation precede robust Aβ deposition in a mouse model of Alzheimer's disease

Hanyan Li, Zhuoyang Zhao, Aline Fassini, Han K. Lee, Reese J. Green, Stephen N. Gomperts

The paper identifies impaired hippocampal circuit function in a mouse model of Alzheimer's disease before Aβ deposition, highlighting issues in theta-gamma oscillations and place cell reactivation during sleep.

Scientific Reports · Jul 1, 2025Peer-reviewedNeuroscience

Neuroprotection of low dose carbon monoxide in Parkinson's disease models commensurate with the reduced risk of Parkinson's among smokers

K. N. Rose, Musab M. Zorlu, Aline Fassini, H Lee, Waijiao Cai, X. Xue, Sung‐Han Lin, Pia Kivisäkk, Michael A. Schwarzschild, Xiqun Chen, Stephen N. Gomperts

The paper shows that low-dose carbon monoxide reduces Parkinson's disease pathology in rodent models by activating HO-1, similar to the protective effect observed in smokers.

npj Parkinson s Disease · Aug 22, 2024Peer-reviewedNeuroscience