Heat-induced seizures, premature mortality, and hyperactivity in a novel Scn1a nonsense model for Dravet syndrome
Anat Mavashov, Marina Brusel, Jiaxing Liu, Victoria Woytowicz, Haneui Bae, Ying-Hsin Chen, Vardhan S. Dani, Elena Cardenal‐Muñoz, Vittoria Spinosa, José Ángel Aibar, Moran Rubinstein
This paper introduces a novel Dravet syndrome mouse model with a Scn1a R613X nonsense mutation, showing seizures, premature death, and hyperactivity.
Frontiers in Cellular Neuroscience · May 3, 2023Peer-reviewedNeuroscience