Author

Ying-Hsin Chen

Case Western Reserve University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Anat MavashoviD· 1 shared Andrea Gilmozzi· 1 shared Elena Cardenal‐MuñoziD· 1 shared Haneui Bae· 1 shared Jeff M. ColleriD· 1 shared Jiaxing LiuiD· 1 shared Jingdong ChengiD· 1 shared José Ángel AibariD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Anat MavashovORCID

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2 papers

Recent·Most cited

Heat-induced seizures, premature mortality, and hyperactivity in a novel Scn1a nonsense model for Dravet syndrome

Anat Mavashov, Marina Brusel, Jiaxing Liu, Victoria Woytowicz, Haneui Bae, Ying-Hsin Chen, Vardhan S. Dani, Elena Cardenal‐Muñoz, Vittoria Spinosa, José Ángel Aibar, Moran Rubinstein

This paper introduces a novel Dravet syndrome mouse model with a Scn1a R613X nonsense mutation, showing seizures, premature death, and hyperactivity.

Frontiers in Cellular Neuroscience · May 3, 2023Peer-reviewedNeuroscience

The Ccr4-Not complex monitors the translating ribosome for codon optimality

Robert Buschauer, Yoshitaka Matsuo, Takato Sugiyama, Ying-Hsin Chen, Najwa Alhusaini, Thomas J. Sweet, Ken Ikeuchi, Jingdong Cheng, Yasuko Matsuki, Risa Nobuta, Andrea Gilmozzi, Otto Berninghausen, Petr Těšina, Thomas A. Becker, Jeff M. Coller, , Roland Beckmann

The paper shows the Ccr4-Not complex interacts with the ribosome's E-site when codon optimality is low, linking translation efficiency to mRNA stability.

Science · Apr 16, 2020Peer-reviewedMolecular Biology