Dysregulation of Neuropilin-2 Expression in Inhibitory Neurons Impairs Hippocampal Circuit Development Leading to Autism-Epilepsy Phenotype
Deepak Subramanian, Carol Eisenberg, Andrew Huang, Jiyeon Baek, Haniya Naveed, Samiksha Komatireddy, Michael W. Shiflett, Tracy S. Tran, Vijayalakshmi Santhakumar
This study shows that disrupting Nrp2 in interneuron precursors leads to ASD-like behaviors and increased seizure risk in mice.
Molecular Psychiatry · Nov 22, 2024Peer-reviewedNeuroscience