CRISPR screen decodes SWI/SNF chromatin remodeling complex assembly
Hanna Schwaemmle, Hadrien Soldati, Nikolaos M. R. Lykoskoufis, Mylène Docquier, Alexandre Hainard, Simon M. G. Braun
The paper identifies Mlf2 and Rbm15 as regulators of SWI/SNF complex activity through CRISPR screening in mouse embryonic stem cells, revealing their roles in chromatin remodeling and m6A RNA methylation.
Nature Communications · May 30, 2025Peer-reviewedMolecular Biology