Author

Hadrien Soldati

University of Geneva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Cell Biology· 1 Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:cell type annotation· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Simon M. G. BrauniD· 5 shared Nikolaos M. R. LykoskoufisiD· 2 shared Alexandre HainardiD· 1 shared Amanpreet Singh ChawlaiD· 1 shared Aurélie Caillon· 1 shared Britt NakkeniD· 1 shared Elien De BousseriD· 1 shared Hanna Schwaemmle· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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5 shared papersMolecular Biology

Simon M. G. BraunORCID

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Author profile →

5 papers

Recent·Most cited

A Glycosylation-Dependent Checkpoint Restrains Intestinal Intra-Epithelial Lymphocyte Activation

Liqing Cheng, Niccolò Bianchi, Hadrien Soldati, Ludivine Bersier, Maximilien Evrard, Aurélie Caillon, Amanpreet Singh Chawla, Britt Nakken, Péter Szodoray, Elien De Bousser, Nele Festjens, Tatiana V. Petrova, Sylvain Lemeille, Laura K. Mackay, Nico Callewaert, , Simone Becattini

This study identifies GCNT2 as a glycosylation-dependent checkpoint that restrains intestinal intra-epithelial lymphocyte (IEL) activation by modifying CD45 and dampening TCR signaling.

bioRxiv · Jun 16, 2026 · PreprintImmunology

Distinct epigenetic and metabolic states reflect the regional identity of adult neural stem cells and prime their fate

Valentina Scandella, Nikolaos M. R. Lykoskoufis, Hadrien Soldati, Livia Di Martino, Tony Teav, Héctor Gallart‐Ayala, Julijana Ivanišević, Simon M. G. Braun, Marlen Knobloch

This study identifies niche-specific chromatin and metabolic states in adult mouse neural stem cells that influence their neuronal fate potential.

bioRxiv · Jan 26, 2026 · PreprintCell Biology

Redundancy masks functional specificity of SMARCD paralogs in neurodevelopment

YounJu So, Hadrien Soldati, Laurine Anselme, Simon M. G. Braun

The paper shows that SMARCD paralogs exhibit functional redundancy but also specialized roles in neurodevelopment, with SMARCD3 uniquely regulating oxidative phosphorylation.

bioRxiv · Dec 7, 2025 · PreprintMolecular Biology

CRISPR screen decodes SWI/SNF chromatin remodeling complex assembly

Hanna Schwaemmle, Hadrien Soldati, Nikolaos M. R. Lykoskoufis, Mylène Docquier, Alexandre Hainard, Simon M. G. Braun

The paper identifies Mlf2 and Rbm15 as regulators of SWI/SNF complex activity through CRISPR screening in mouse embryonic stem cells, revealing their roles in chromatin remodeling and m6A RNA methylation.

Nature Communications · May 30, 2025Peer-reviewedMolecular Biology

High throughput screening identifies SOX2 as a Super Pioneer Factor that inhibits DNA methylation maintenance at its binding sites

Ludovica Vanzan, Hadrien Soldati, Victor Ythier, Santosh Kumar Anand, Simon M. G. Braun, Nicole Jane Francis, Rabih Murr

The paper identifies SOX2 as a super pioneer factor that inhibits DNA methylation maintenance at its binding sites through passive demethylation during replication.

Nature Communications · Jun 7, 2021Peer-reviewedGenetics