Disruption of the insulin signaling pathway in C. elegans dramatically increases male longevity and enhances reproductive health late in life
Rose S. Al-Saadi, Hannah B. Lewack, Patrick C. Phillips
This study shows that disrupting the insulin signaling pathway in male C. elegans significantly increases lifespan and improves reproductive health late in life.
bioRxiv · Nov 4, 2025 · PreprintGenetics