Cross-feeding reshapes interactions between antibiotic stressors through metabolic feedbacks
Xianyi Xiong, Tong Zhou, Ave T. Bisesi, Tsz Fung Wong, Jeremy M Chacon, Hannah Furseth, Lauren Slavic, Paul C. Blainey, William R. Harcombe
The paper shows that cross-feeding between bacteria changes how antibiotic combinations affect growth, shifting interactions toward antagonism due to metabolic feedbacks.
bioRxiv · Oct 22, 2026 · PreprintMicrobiology