A molecular circuit regulates fate plasticity in emerging and adult AT2 cells
Amitoj Singh Sawhney, B. Deskin, Junming Cai, Daniel F. Gibbard, Gibran Ali, Annika Utoft, Xianmei Qi, Aaron Olson, Hannah Hausman, Liberty Sabol, Shannon Holmberg, Ria Shah, Rachel Warren, Stijn De Langhe, Zintis Inde, , Douglas Brownfield
The paper identifies a molecular circuit involving C/EBP and Dlk1 that regulates fate plasticity in AT2 cells during lung development and injury.
Nature Communications · Oct 14, 2025Peer-reviewedDevelopmental Biology