Author

Hannah Trost

Beckman Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Arianna Merkell· 2 shared Felicia Wednesday LopezcoloradoiD· 2 shared Jeremy M. StarkiD· 2 shared Alyssa N. CoyneiD· 1 shared Amnon HareliD· 1 shared Benjamin L. ZaepfeliD· 1 shared Boris Fitchman· 1 shared Clive Niels SvendseniD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMolecular Biology

Arianna Merkell

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3 papers

Recent·Most cited

Functions of PMS2 and MLH1 important for regulation of divergent repeat-mediated deletions

Hannah Trost, Felicia Wednesday Lopezcolorado, Arianna Merkell, Jeremy M. Stark

The paper investigates the roles of MLH1 and PMS2 in suppressing divergent repeat-mediated deletions and resolving sequence divergence polarity, finding distinct functions for these processes.

DNA repair · Nov 26, 2024Peer-reviewedMolecular Biology

Mismatch resolution for repeat-mediated deletions show a polarity that is mediated by MLH1

Hannah Trost, Arianna Merkell, Felicia Wednesday Lopezcolorado, Jeremy M. Stark

The paper identifies MLH1's role in suppressing repeat-mediated deletions and promoting directional mismatch resolution in mouse cells.

Nucleic Acids Research · Jan 4, 2023Peer-reviewedMolecular Biology

G4C2 repeat RNA mediates the disassembly of the nuclear pore complex in C9orf72 ALS/FTD

Alyssa N. Coyne, Benjamin L. Zaepfel, Lindsey R. Hayes, Boris Fitchman, Yuval Salzberg, Kelly Bowen, Hannah Trost, Frank Rigo, Amnon Harel, Clive Niels Svendsen, Dhruv Sareen, Jeffrey D. Rothstein

The paper identifies POM121 as a critical nucleoporin affected by C9orf72 repeat RNA, leading to nuclear pore complex disassembly and neuronal toxicity in ALS/FTD.

bioRxiv · Feb 13, 2020 · PreprintNeuroscience