Jeremy M. Stark

This study characterizes MRI/CYREN's structure and function in NHEJ, showing its disordered regions bind Ku80 and multimerization enhances DNA repair efficiency.

The paper investigates the genetic interactions between 53BP1/RIF1 and DNA-PKcs in DNA double strand break repair, revealing distinct roles in different repair outcomes.

The paper examines the roles of PAXX and MRI in chromosomal end joining during C-NHEJ, showing their distinct contributions and interactions with DNA-PKcs and XLF.

The paper investigates the roles of MLH1 and PMS2 in suppressing divergent repeat-mediated deletions and resolving sequence divergence polarity, finding distinct functions for these processes.

The paper identifies MLH1's role in suppressing repeat-mediated deletions and promoting directional mismatch resolution in mouse cells.

The paper shows DNAPKcs is critical for blunt DNA end joining when XLF is weakened, but less important under normal conditions.