Conserved copper(I)-binding auxiliary domains link virulence-associated LPMOs to copper homeostasis in the intestinal environment
Eirik G. Kommedal, Hanne Berggreen, Synnøve Elisa Rønnekleiv, Henrik Vinther Sørensen, Ane Runningen, Yong Zhou, Ute Krengel, Åsmund K. Røhr, Vincent G. H. Eijsink, Zarah Forsberg
The paper shows that copper(I)-binding domains in LPMOs from intestinal pathogens are linked to virulence and copper homeostasis in the gut.
bioRxiv · Aug 6, 2026 · PreprintBiochemistry