Comparative Performance of Two Whole Genome Capture Methodologies on Ancient DNA Illumina Libraries
Maria Avila-Arcos, Marcela Sandoval-Velasco, Hannes Schroeder, Meredith L Carpenter, Anna-Sapfo Malaspinas, Nathan Wales, Fernando Peñaloza, Carlos D Bustamante, M. Thomas P Gilbert
This study compares two whole genome capture methods on ancient DNA libraries, finding that bait length affects enrichment and that WGC may bias against shorter molecules in single-stranded protocols.
Methods in Ecology and Evolution · Mar 31, 2015Peer-reviewedGenomics