MicrobiologybioRxiv
Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques
Ziyu Wen, Pingchao Li, Yue Yuan…·Caijun Sun
This study develops a HSV-vectored therapeutic vaccine that reactivates SIV latency and elicits immune responses, delaying viral rebound in SIV-infected macaques.