An intron-based timer for circadian rhythms
Ye Yuan, Amanda Linskens, Rafael de Gouvea, Haokai Liu, Yangbo Xiao, Smriti Suresh, Irene Hu, Swathi Yadlapalli
The paper identifies an intron in the Drosophila timeless gene that acts as an RNA-based timer regulating circadian period length through nuclear retention of mRNA.
bioRxiv · Oct 27, 2025 · PreprintMolecular Biology