LysM: a bacterial self-encoded peptidoglycan hydrolase as an antimicrobial and anti-biofilm agent for Gram-negative nosocomial pathogens
Yu Zhang, Dejian Liu, Min Zhao, Lanxin Wang, Yanhong Huang, Haoyu Liu, Jingchao Zhang, Bo Ma, Di Wang, Kun Zhao, Jintao Liu, Liang Li, Luyan zulie Ma
This paper identifies LysM, a bacterial enzyme with broad-spectrum antimicrobial and anti-biofilm activity against Gram-negative pathogens, and shows it can enhance antibiotic efficacy.
bioRxiv · Oct 21, 2026 · PreprintMicrobiology