Author

Liang Li

The University of Texas MD Anderson Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 2 Biophysics· 1 Developmental Biology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 3 Assay:spatial transcriptomics· 2 Research Focus:cell type annotation· 1 Research Focus:deconvolution· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Anirban MaitraiD· 1 shared Anna Wu Chen· 1 shared Bailey Roemer· 1 shared Bo MaiD· 1 shared Daniel Adolfo· 1 shared Dejian LiuiD· 1 shared Dexin Chen· 1 shared Di Wang· 1 shared

Activity by Year

2024-2026 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

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1 shared paperBioinformatics

Anirban MaitraORCID

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6 papers

Recent·Most cited

Ferroptosis of selective progenitor cell types during embryogenesis ensures proper organ morphogenesis

Montasir Elahi, Shicong Song, Wei-Bin Shen, Anna Wu Chen, Md Mahadi Hassan, Mohammad Sazzadul Islam, E. Albert Reece, Robin Roychaudhuri, Guanglei Wang, Lihua Zeng, Jin-Gu Lee, Irina Burd, Hangnoh Lee, Qitao Ran, Liang Li, , Peixin Yang

This study identifies ferroptosis in embryonic lung and kidney progenitor cells, showing its role in organ morphogenesis through genetic manipulation of Gpx4.

bioRxiv · Nov 5, 2026 · PreprintDevelopmental Biology

LysM: a bacterial self-encoded peptidoglycan hydrolase as an antimicrobial and anti-biofilm agent for Gram-negative nosocomial pathogens

Yu Zhang, Dejian Liu, Min Zhao, Lanxin Wang, Yanhong Huang, Haoyu Liu, Jingchao Zhang, Bo Ma, Di Wang, Kun Zhao, Jintao Liu, Liang Li, Luyan zulie Ma

This paper identifies LysM, a bacterial enzyme with broad-spectrum antimicrobial and anti-biofilm activity against Gram-negative pathogens, and shows it can enhance antibiotic efficacy.

bioRxiv · Oct 21, 2026 · PreprintMicrobiology

New solid-state optical pH sensors for cell analysis

Liang Li

The paper develops new solid-state optical pH sensors for real-time monitoring of extracellular acidification in cultured cancer cells and 3D spheroids.

bioRxiv · Aug 9, 2026 · PreprintBiophysics

Regulation of Pacemaker Current in the Sinoatrial Node by Zonula Occludens-1

Rui Zhang, Sarah Teboull, Dexin Chen, Pexin He, Seho Kim, Liang Li, Daniel Adolfo, Terence W. Gee, Robert S. Ross, Joshua I. Goldhaber

This study investigates the role of ZO-1 in sinoatrial node automaticity and finds that its loss reduces pacemaker current and impairs atrial conduction, leading to bradyarrhythmia.

bioRxiv · May 21, 2026 · PreprintPhysiology

UniST: A Unified Computational Framework for 3D Spatial Transcriptomics Reconstruction

Lan Shui, Yunhe Liu, Idania Carolina Lubo Julio, Jean Rene V. Clemenceau, Xen Ping Hoi, Yibo Dai, Wei Lü, Jimin Min, Khaja B. Khan, Bailey Roemer, Mei Jiang, Rebecca E. Waters, Karen Colbert, Anirban Maitra, Max Wintermark, , Ziyi Li

UniST reconstructs dense 3D spatial transcriptomics data from sparse serial sections, restoring structural continuity and biologically meaningful expression patterns in multiple tissue contexts.

bioRxiv · Mar 16, 2026 · PreprintBioinformatics

Delineating the Spatial Patterns of Cell Type-Specific Stemness Using a Statistical Deconvolution Model

Eric J. Li, Liang Li, Ziyi Li

The paper develops a statistical deconvolution model to estimate cell type-specific stemness in spatial transcriptomics data and applies it to breast cancer data.

bioRxiv · Dec 29, 2024 · PreprintBioinformatics