NAD+-dependent deacetylase SIRT1 is essential for meiotic progression and controls repair-recombination efficiency
Harshita Kaul, Shaunak Deota, Amit Fulzele, Anne Gonzalez de Peredo, Ullas Kolthur‐Seetharam
This study identifies SIRT1 as essential for meiotic progression and shows it regulates repair-recombination efficiency by controlling crossover frequency and checkpoint responses.
bioRxiv · Jun 10, 2019 · PreprintDevelopmental Biology