Neolithic introgression of IL23R-related protection against chronic inflammatory bowel diseases in modern Europeans
Ben Krause‐Kyora, Nicolas Antonio da Silva, Elif Kaplan, Daniel Kolbe, Sabine Schade-Lindig, Joachim Wahl, Carola Berszin, Michael Francken, Irina Görner, Kerstin Schierhold, Joachim Pechtl, Gisela Grupe, Johannes Müller, Inken Wohlers, Hauke Busch, , Stefan Schreiber
The paper traces the origin and spread of the IL23R variant rs11209026-A in Europe, linking its frequency changes to Neolithic agricultural practices and its protective role against inflammatory bowel diseases.
EBioMedicine · Feb 8, 2025Peer-reviewedEvolutionary Biology