The Epigenetic Factor PHF13 Governs Trophoblast Stemness and Differentiation
Sheng Liu, Lei Liu, Jiayu Meng, Elena Sadovsky, Keyi Huang, Heather L. Sorenson, Tianjiao Chu, Yoel Sadovsky, Yingshi Ouyang
This study identifies PHF13 as a chromatin regulator critical for trophoblast stemness and differentiation, showing its role in maintaining stemness and restricting differentiation through gene regulatory networks.
bioRxiv · Mar 17, 2026 · PreprintMolecular Biology